Description
INTRODUCTION ABOUT RABIKEM DSR 30/20MG CAPSULE
RABIKEM DSR 30/20MG CAPSULE is used to manage Gastro-Esophageal Reflux Disease (GERD) among patients who have not responded adequately to rabeprazole alone. It is a combination of Domperidone and Rabeprazole which belongs to the group of medicines called Dopamine Antagonists and Proton pump inhibitors respectively. It can also be used to manage peptic ulcers caused by H. pylori infection or NSAIDs use.
Along management with RABIKEM DSR 30/20MG CAPSULE, try to eat less spicy foods and drink plenty of water. Avoid smoking or alcohol consumption as it may aggravate your existing condition. Patients receiving long-term management with the medicine should be kept on regular surveillance to rule out the risk of hypomagnesaemia (decreased magnesium levels in blood) and bone fracture, predominantly in the elderly patients and in patients with other recognized risk factors.
Before taking RABIKEM DSR 30/20MG CAPSULE inform your doctor if you have any liver, kidney or heart problems. Your doctor may reduce the dose or suggest an alternative therapy. It is not recommended for use in pregnant or breastfeeding women and in children (aged less than 18 years). It should be used with caution in elderly patients (above 65 years of age). The most common side effects are nausea, vomiting, stomach pain, diarrhea or constipation. Consult your doctor if any of these above side effects worsen.
USES OF RABIKEM DSR 30/20MG CAPSULE
It is used to manage:
- peptic ulcer
- Gastro-Esophageal Reflux Disease (GERD)
HOW RABIKEM DSR 30/20MG CAPSULE WORKS
RABIKEM DSR 30/20MG CAPSULE reduces stomach ulcers and acid reflux, where Rabeprazole acts by inhibiting the secretions of stomach acid and Domperidone acts by increasing bowel movements and facilitating gastric emptying, thus leading to rapid symptom relief and healing of stomach ulcers and esophageal lesions.
DIRECTIONS FOR USE
- Take RABIKEM DSR 30/20MG CAPSULE as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition
SIDE EFFECTS OF RABIKEM DSR 30/20MG CAPSULE
Common side effects of RABIKEM DSR 30/20MG CAPSULE:
- nausea, vomiting
- diarrhea, constipation, stomach pain, flatulence
- cough, sore throat, runny nose
- back pain
- headache, dizziness
- dry mouth
- benign polyps in the stomach
- indigestion, belching in the stomach (excess air accumulation in the stomach)
- urinary tract infection
Stop taking RABIKEM DSR 30/20MG CAPSULE and contact your doctor immediately if you experience the following side effects:
- severe allergic reaction (sudden wheezing, swelling of lips, face or body, rash, fainting or difficulties swallowing)
- symptoms of liver problems (yellow skin, dark urine and tiredness)
- severe skin reactions such as erythema multiforme, stevens-johnson syndrome or toxic epidermal necrolysis (reddening of skin with blisters or peeling and may be associated with a high fever and joint pains, also severe blisters and bleeding in the lips, eyes, mouth, nose and genitals)
- seizures
- involuntary movements of the face or arms and legs, excessive trembling, excessive muscle stiffness or muscle spasm
- heart rhythm disorders (rapid or irregular heartbeat)
WARNING & PRECAUTIONS
PREGNANCY
Contraindicated
RABIKEM DSR 30/20MG CAPSULE is not recommended for use in pregnant women.
BREASTFEEDING
Contraindicated
RABIKEM DSR 30/20MG CAPSULE is not recommended for use in breast-feeding women.
DRIVING AND USING MACHINES
Use with Caution
Do not drive or operate any machines if you experience sleepiness, confusion or less control over your movements.
ALCOHOL
Consult your doctor
Avoid consumption of alcohol while taking RABIKEM DSR 30/20MG CAPSULE, as it could aggravate your existing condition.
KIDNEY
Contraindicated
RABIKEM DSR 30/20MG CAPSULE is not recommended for use in patients with kidney impairment.
LIVER
Consult your doctor
RABIKEM DSR 30/20MG CAPSULE is not recommended for use in patients with moderate or severe liver impairment and it should be used with caution in patients with liver problems.
ALLERGY
Contraindicated
Do not take RABIKEM DSR 30/20MG CAPSULE if you are allergic to Domperidone or Rabeprazole or any other ingredients of this medicine.
HEART DISEASE
Contraindicated
RABIKEM DSR 30/20MG CAPSULE is not recommended for use in patients with heart problems such as prolongation of QT interval or congestive heart failure.
USE IN PEDIATRICS
Contraindicated
RABIKEM DSR 30/20MG CAPSULE is not recommended for use in children and adolescents (aged less than 18 years) due to lack of safety and effectiveness.
USE IN GERIATRICS
Use with Caution
RABIKEM DSR 30/20MG CAPSULE should be taken with caution in elderly patients (aged 65 years or above).
OTHERS
RABIKEM DSR 30/20MG CAPSULE is not recommended for use if you:
- Have bloody stools or bleeding in the gut
- Have blockage or tear in the intestines
- Have severe fluid or electrolyte disturbances
- Have prolactinoma
- Have phenylketonuria
- Have problem that causes low levels of potassium or magnesium or high levels of potassium in the blood
- Have hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption
Before taking RABIKEM DSR 30/20MG CAPSULE, inform your physician if you:
- Have osteoporosis
- Have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression)
- Are going to test Chromogranin A level
INTERACTIONS
A. Drug-Drug interactions:
Before taking the medicine, inform to your doctor if you are taking any of these medicines:
- Prokinetic agent (Ex. Cisapride, dolasetron, prucalopride, diphemanil)
- Cardiac glycosides (Ex. Digoxin, apomorphine, disopyramide, hydroquinidine, quinidine, amiodarone, dofetilide, dronedarone, ibutilide, sotalol, diltiazem or verapamil)
- Ant-viral agents (Ex. Atazanavir, nelfinavir, saquinavir, Telaprevir)
- Antipsychotics (Ex. Haloperidol, pimozide, sertindole)
- Antidepressants (Ex. Escitalopram or citalopram)
- Antibiotics (Ex. Moxifloxacin, erythromycin, levofloxacin, clarithromycin, telithromycin or amoxicillin)
- Antimalarials (Ex. Halofantrine, lumefantrine)
- Antihistamines (Ex. Mizolastine, mequitazine)
- Nonsteroidal antiestrogens (Ex. Toremifene, vandetanib, vincamine, erlotinib, dasatinib, nilotinib)
- Antimetabolites (Ex. Methotrexate)
- Antihypertensives (Ex. Bepridil)
- Opioid narcotics (Ex. Methadone)
- Iron salts
- Immunosuppressants (Ex. Tacrolimus or mycophenolate mofetil)
- Antifungals (Ex. Ketoconazole, itraconazole)
- Anti-infective (Ex. Pentamidine)
- Anticoagulants (Ex. Warfarin)
Overdosage:
If you or anyone else take too much of RABIKEM DSR 30/20MG CAPSULE, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms are altered consciousness, agitation, convulsions, disorientation, sleepiness and extrapyramidal reactions (such as rigidity, tremor, drooling).
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